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Recent advances in myeloid-derived suppressor cell biology

Mahmoud Mohammad Yaseen, Nizar Mohammad Abuharfeil, Homa Darmani, Ammar Daoud

《医学前沿（英文）》 2021年第15卷第2期页码 232-251 doi: 10.1007/s11684-020-0797-2

摘要： In recent years, studying the role of myeloid-derived suppressor cells (MDSCs) in many pathological inflammatory conditions has become a very active research area. Although the role of MDSCs in cancer is relatively well established, their role in non-cancerous pathological conditions remains in its infancy resulting in much confusion. Our objectives in this review are to address some recent advances in MDSC research in order to minimize such confusion and to provide an insight into their function in the context of other diseases. The following topics will be specifically focused upon: (1) definition and characterization of MDSCs; (2) whether all MDSC populations consist of immature cells; (3) technical issues in MDSC isolation, estimation and characterization; (4) the origin of MDSCs and their anatomical distribution in health and disease; (5) mediators of MDSC expansion and accumulation; (6) factors that determine the expansion of one MDSC population over the other; (7) the Yin and Yang roles of MDSCs. Moreover, the functions of MDSCs will be addressed throughout the text.

关键词： non-human primates (rhesus macaques) myeloid-derived pro-inflammatory cells (MDPCs) autoimmune disorders alloimmune responses pregnancy mature MDSCs multiple sclerosis Yin-Yang law of MDSCs

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分形方法导出改进的牛顿第二定律及万有引力定律

付昱华

《中国工程科学》 2003年第5卷第6期页码 55-58

摘要：

牛顿第二定律及万有引力定律是根据实验结果总结出来的。为了探讨从理论上导出这两个定律的可能性，根据能量守恒定律，给出用变维分形方法针对一个实例（小球沿长斜面滚下）导出改进的牛顿第二定律及万有引力定律的方法。具体给出了适用于实例的常维分形结果：改进的万有引力定律F=-GMm / r^1.99989和改进的牛顿第二定律F=ma^1.01458。

关键词：分形方法牛顿第二定律万有引力定律理论推导

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Improving existing “reaching law” for better discrete control of seismically-excited building structures

Zhijun LI, Zichen DENG

《结构与土木工程前沿（英文）》 2009年第3卷第2期页码 111-116 doi: 10.1007/s11709-009-0022-5

摘要： In this paper, a novel “composite reaching law” was explained in details: 1) the equation of discrete motion for a control system; 2) the design of discrete-time variable structure control. In addition, the model of a three-storey shear-type building structure was used to verify the effectiveness of the discrete variable structure control method. The results of numerical example analysis of the model show that the control law can effectively reduce the peak value of seismic response of the building structure and the chattering effect of the control system.

关键词： discrete-time variable structure control composite reaching law chattering effect saturated control law

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Gene delivery into isolated

Nan Zheng, Ziyuan Song, Yang Liu, Lichen Yin, Jianjun Cheng

《化学科学与工程前沿（英文）》 2017年第11卷第4期页码 521-528 doi: 10.1007/s11705-017-1612-8

摘要： The application of gene delivery materials has been mainly focused on mammalian cells while rarely extended to plant engineering. Cationic polymers and lipids have been widely utilized to efficiently deliver DNA and siRNA into mammalian cells. However, their application in plant cells is limited due to the different membrane structures and the presence of plant cell walls. In this study, we developed the cationic, -helical polypeptide that can effectively deliver DNA into both isolated protoplasts and intact leaves. The PPABLG was able to condense DNA to form nanocomplexes, and they exhibited significantly improved transfection efficiencies compared with commercial transfection reagent Lipofectamine 2000 and classical cell penetrating peptides such as poly(L-lysine), HIV-TAT, arginine9, and poly(L-arginine). This study therefore widens the utilities of helical polypeptide as a unique category of gene delivery materials, and may find their promising applications toward plant gene delivery.

关键词： α-helical polypeptide plant gene delivery protoplast intact leaves transfection

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How did Archimedes discover the law of buoyancy by experiment?

Hidetaka KUROKI

《机械工程前沿（英文）》 2016年第11卷第1期页码 26-32 doi: 10.1007/s11465-016-0368-z

摘要：

After Archimedes and Vitruvius era, for more than 2000 years, it has been believed that the displaced water measurement of golden crown is impossible, and at his Eureka moment, Archimedes discovered the law of buoyancy (Proposition 7 of his principles) and proved the theft of a goldsmith by weighing the golden crown in water.

A previous study showed that a small amount of displaced water was able to be measured with enough accuracy by the introduced method. Archimedes measured the weight of displaced water. He did not find the law of buoyancy but rather specific gravity of things at the moment.

After which, Archimedes continued to measure the specific gravity of various solids and fluids. Through these measurements, he reached the discovery of the law of buoyancy directly by experiment. In this paper, the process to the discovery of Archimedes’ principle (Proposition 5) is presented.

关键词： Archimedes’ principle buoyancy specific gravity Eureka Vitruvius displaced water balance floating body

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Erratum to: Electrochemical removal of nitrate in industrial wastewater

Dong Xu, Yang Li, Lifeng Yin, Yangyuan Ji, Junfeng Niu, Yanxin Yu

《环境科学与工程前沿（英文）》 2018年第12卷第3期 doi: 10.1007/s11783-018-1038-7

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A novel approach in preparing polymer/nano-CaCO composites

LIU Zhengying, YU Runze, YANG Mingbo, FENG Jianmin, YANG Wei, YIN Bo

《化学科学与工程前沿（英文）》 2008年第2卷第1期页码 115-122 doi: 10.1007/s11705-008-0020-5

摘要： An novel compounding process using nano-CaCO aqueous suspension for preparing polymer/nano-CaCO composites with nanoparticles dispersed at the nanoscale is reported. The process is called the mild mixing method. In this method, the pre-dispersed nanoparticle suspensions are blended with melting polymers in a weak shearing field using an extruder, followed by removing the water from the vent. The four typical polymeric nanocomposites were prepared by mild mixing method. The dispersion of nano-CaCO in the matrix of the polymer at the nanoscale was confirmed by scanning electron microscopy (SEM). The molecular weights of polycarbonate (PC) and its nanocomposite showed that the degradation had not occurred during the mild mixing processing. The mechanical properties of the composite with 1.5 wt-% nano-CaCO improve slightly. It proved that this approach is suitable for the preparation of nanocomposites based on both polar and non-polar polymers.

关键词： preparation suitable nano-CaCO pre-dispersed nanoparticle processing

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China’s Ministry of Environmental Protection Adopted Draft Amendment to the Law on Prevention and Control

Fu Sun,Yi Liu

《环境科学与工程前沿（英文）》 2016年第10卷第6期 doi: 10.1007/s11783-016-0890-6

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Electrochemical removal of nitrate in industrial wastewater

Dong Xu, Yang Li, Lifeng Yin, Yangyuan Ji, Junfeng Niu, Yanxin Yu

《环境科学与工程前沿（英文）》 2018年第12卷第1期 doi: 10.1007/s11783-018-1033-z

摘要： A number of recent studies have demonstrated that electrochemical technologies, including electroreduction (ER), electrocoagulation (EC), and electrodialysis (ED), are effective in nitrate elimination in wastewater due to their high reactivity. To obtain the maximal elimination efficiency and current efficiency, many researchers have conducted experiments to investigate the optimal conditions (i.e., potential, current density, pH value, plate distance, initial nitrate concentration, electrolyte, and other factors) for nitrate elimination. The mechanism of ER, EC and ED for nitrate removal has been fully elucidated. The ER mechanism of nitrate undergoes electron transfer and hydrogenation reduction. The EC pathways of nitrate removal include reduction, coagulation and flotation. The ED pathways of nitrate include redox reaction and dialysis. Although the electrochemical technology can remove nitrate from wastewater efficiently, many problems (such as relatively low selectivity toward nitrogen, sludge production and brine generation) still hinder electrochemical treatment implementation. This paper critically presents an overview of the current state-of-the-art of electrochemical denitrification to enhance the removal efficiency and overcome the shortages, and will significantly improve the understanding of the detailed processes and mechanisms of nitrate removal by electrochemical treatment and provide useful information to scientific research and actual practice.

关键词： Nitrate removal Electroreduction Electrocoagulation Electrodialysis

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Development and application of innovative technologies for drinking water quality assurance in China

QU Jiuhui, YIN Chengqing, YANG Min, LIU Huijuan

《环境科学与工程前沿（英文）》 2007年第1卷第3期页码 257-269 doi: 10.1007/s11783-007-0044-y

摘要： The continuously deteriorating quality of source water is threatening the safety of drinking water in China. Various efforts have been made to update water treatment processes to decrease the pollution problems of drinking water, such as protection of drinking water sources, enhancement of conventional treatment processes, and development of new or advanced treatment technologies. This paper reviews a variety of protection and remediation methods for drinking water sources, development and application of drinking water treatment technologies, new technologies for special pollutants removal from groundwater, and the latest research progress on water distribution systems in China. treatment plant improvement is the key to ensure the quality of drinking water. There have been many researches on innovative treatment technologies in China and they have been applied in quite a number of water treatment plants. These innovations include key technique development and combination of technologies in the scope of economic optimization. On the basis of water quality from the plant, the distribution system is also important. This paper describes the latest development in the above respects.

关键词： advanced treatment economic optimization Various enhancement improvement

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Why does environmental compliance cost more than penalty? —A legal analysis on environmental acts of enterprises in China

DONG Hongwei

《环境科学与工程前沿（英文）》 2007年第1卷第4期页码 434-442 doi: 10.1007/s11783-007-0069-2

摘要： In the environmental protection field of China, due to lower law-breaking cost but higher law-abiding cost , it is a common case that the enterprise chooses to break through the law on purpose. The punishment to the unlawful pr

关键词： law-abiding punishment environmental protection law-breaking enterprise

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贯彻《节能法》推动节能工作

傅志寰

《中国工程科学》 2008年第10卷第12期页码 13-16

摘要：

近年来我国能源消费增长快、利用效率低的问题比较突出，原有《节能法》已经不能适应当前节能工作的要求。为了推动全社会的节约能源工作，全国人大今年修订了这部法律。文章介绍了修订后的《节能法》基本思路、主要内容和实施后的初步效果。

关键词：法律能源节约

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我国水污染防治法综合评估研究

侯立安,徐祖信,尹海龙,张林

《中国工程科学》 2022年第24卷第5期页码 126-136 doi: 10.15302/J-SSCAE-2022.05.015

摘要：

全面贯彻实施新修订的《中华人民共和国水污染防治法》对打好污染防治攻坚战和建设美丽中国具有重要意义。本文首先评估了水污染防治法2018 年1 月1 日施行以来取得的八个方面成效，在此基础上剖析了水污染防治法实施中存在的问题，主要体现在水环境管理体制机制、水污染执法监管、饮用水水源保护和地下水污染防治、水污染防治主要工作四个方面。对此，提出了近期亟需加强的四方面对策措施，通过以流域统筹、完善河长制考核和水环境质量改善为总抓手，在管理体系、执法能力、水源保护和污染防治四个方面形成系统性合力，深入推进工业废水达标排放、城镇管网截污治理、市政污泥资源化处理处置、农村污水低碳经济处理和农村面源污染防治，强化依法治水和科学治水。

关键词：水污染防治河长制环境管理环境标准水源保护

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Role of chemerin/CMKLR1 in the maintenance of early pregnancy

Xuezhou Yang, Junning Yao, Qipeng Wei, Jinhai Ye, Xiaofang Yin, Xiaozhen Quan, Yanli Lan, Hui Xing

《医学前沿（英文）》 2018年第12卷第5期页码 525-532 doi: 10.1007/s11684-017-0577-9

摘要：

Chemerin is a cytokine that attracts much attention in the reproductive process. This study aimed to explore the effects of chemerin and its receptor chemokine-like receptor 1 (CMKLR1) on the maintenance of early pregnancy. The expression levels of chemerin and CMKLR1 in the decidua tissues of 20 early normal pregnant women and 20 early spontaneous abortion women were examined by Western blot and real-time polymerase chain reaction analyses. CMKLR1 receptor antagonist (α-NETA) was then intrauterinely injected into normal pregnant mice model to assess its effect on the outcome of pregnancy and the phosphorylation rate of ERK1/2 in decidua tissues. We found that the expression level of chemerin in women who had experienced early spontaneous abortion was lower than in those who had experienced normal early pregnancy (P<0.01); conversely, CMKLR1 expression was higher in the former than in the latter (P<0.01). In a pregnant-mouse model, the embryo resorption rate of α-NETA group was higher than that in the negative control group (61.5% vs. 10.8%) (P<0.001). Compared with the control group, ERK1/2 phosphorylation in decidua tissues decreased in the α-NETA-treated group (P<0.01). These results suggested that the inhibition of the chemerin/CMKLR1 signaling pathway can lead to the abortion of mouse embryos, and that chemerin/CMKLR1 may play an important role in the maintenance of early pregnancy possibly by regulating ERK1/2 phosphorylation.

关键词： chemerin CMKLR1 early abortion

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Integrated energy storage system based on triboelectric nanogenerator in electronic devices

Xiao Feng, Yang Zhang, Le Kang, Licheng Wang, Chongxiong Duan, Kai Yin, Jinbo Pang, Kai Wang

《化学科学与工程前沿（英文）》 2021年第15卷第2期页码 238-250 doi: 10.1007/s11705-020-1956-3

摘要： The emergence of electronic devices has brought earth-shaking changes to people’s life. However, an external power source may become indispensable to the electronic devices due to the limited capacity of batteries. As one of the possible solutions for the external power sources, the triboelectric nanogenerator (TENG) provides a novel idea to the increasing number of personal electronic devices. TENG is a new type of energy collector, which has become a hot spot in the field of nanotechnology. It is widely used at the acquisition and conversion of mechanical energy to electric energy through the principle of electrostatic induction. On this basis, the TENG could be integrated with the energy storage system into a self-powered system, which can supply power to the electronic devices and make them work continuously. In this review, TENG’s basic structure as well as its working process and working mode are firstly discussed. The integration method of TENGs with energy storage systems and the related research status are then introduced in detail. At the end of this paper, we put forward some problems and discuss the prospect in the future.

关键词： electronic devices triboelectric nanogenerator mechanical energy self-powered system